To this end, the associations between nasal anti-SARS-CoV-2 IgA antibodies responses, virus neutralization at the mucosal surface, and lower risk of developing severe COVID-19 illness provide further support to the clinical significance of assessing and monitoring mucosal immunity in patients with natural SARS-CoV-2 infection and/or in COVID-19 vaccine recipients [17], [18]. The gene discussed is CD79A; the disease is COVID-19.