Using UALCAN and KM plotter tool, transcriptional expression analysis of CTHRC1 and its correlation analysis with the OS duration of the cancer patients showed that CTHRC1 level was significantly (p > 0.05) elevated and associated with the reduced OS duration of the HNSC, KIRC, LIHC, LUAD, STAD, and UCEC patients. The gene discussed is CTHRC1; the disease is cancer.