Moreover, we have also found that CTHRC1 expression was inversely correlated with tumor purity in HNSC, KIRC, LIHC, LUAD, STAD, and UCEC, this knowledge may also help in predicting the clinical outcomes in HNSC, KIRC, LIHC, LUAD, STAD, and UCEC. The gene discussed is CTHRC1; the disease is neoplasm.