Our results revealed the notably elevated CTHRC1 transcriptional level in all these cancer tissues relative to normal control including head and neck squamous cell carcinoma (HNSC), kidney renal clear cell carcinoma (KIRC), liver hepatocellular carcinoma (LIHC), Lung adenocarcinoma (LUAD), stomach adenocarcinoma (STAD), and Uterine corpus endometrial carcinoma (UCEC) (Fig. 1). Here, CTHRC1 is linked to head and neck squamous cell carcinoma.