CTHRC1 and cancer: Our results revealed that CTHRC1 was genetically altered in only 4%, 0.6%, 9%, 4%, 5%, and 6% of the queued HNSC, KIRC, LIHC, LUAD, STAD, and UCEC samples, respectively, and deep amplification genetic abnormality was most frequent in these cancer subtypes (Fig. 13).