CTHRC1 and neoplasm: Analysis results showed that CTHRC1 expression level was negatively related to the tumor purity in HNSC (Rho = − 0.05, p = 2.13e − 01), KIRC (Rho = − 0.192, p = 2.32e − 05), LIHC (Rho = − 0.367, p = 1.91e − 12), LUAD (Rho = − 0.21, p = 2.48e − 06), STAD (Rho = − 0.135, p = 8.25e − 03), and UCEC (Rho = − 0.07, p = 2.30e − 01) (Fig. 15).