Although the total pool of CD127+ CD94− conventional helper ILCs did not increase in frequency, we observed an average 6-fold increase of CD127+CD94+ cells and doubling of CD127−CD94+ NK cells within CD45+ Lamina Propria Mononuclear Cells (LPMCs) of non-inflamed vs. inflamed resection specimen of individuals with Crohn’s disease (Fig. 4a, b). Here, KLRD1 is linked to Crohn disease.