Estimates for haemorrhagic stroke were however opposite compared to estimates for all stroke and ischaemic stroke in individuals treated with insulin, although not statistically significantly different from the lowest eGDR category HRs (95% CI): 1.19 (0.63–2.22), 1.63 (0.46–5.8) and 2.67 (0.45–15.74) (Additional file 1: Figure S4). This evidence concerns the gene INS and Stroke.