Importantly, 5/10 categories with significant NES were also associated with processes involved in DNA repair (DNA replication, homologous recombination, Fanconi anemia pathway, mismatch repair, and nucleotide excision repair), strongly suggesting that aberrant YAP/TAZ expression could be involved in the accumulation of mutations and genomic alterations. This evidence concerns the gene WWTR1 and Fanconi anemia.