In univariate analysis, age, BMI (HR 0.91; 95% CI 0.84–0.98; p = 0.016), malnutrition (HR 3.69; 95% CI 2.11–6.42; p < 0.001), hemodialysis (HR 2.63; 95% CI 1.51–4.58; p < 0.001), prior heart failure, cholinesterase, hs-CRP, albumin (HR 0.43; 95% CI 0.28–0.65; p < 0.001), eGFR, and LVEF were significantly associated with MACCE (Table 3). The gene discussed is ALB; the disease is nutritional deficiency disease.