SLC19A3 gene has been associated with neuropathies including Thiamine responsive encephalopathy type 2 (OMIM #607483), severe psychomotor retardation and progressive atrophy, Wernicke’s-like encephalopathy (OMIM #606152), and Leigh syndrome (OMIM #256000) [23,24]. Here, SLC19A3 is linked to Leigh syndrome.