IPMK and infection: However, the HIV-1CA 5-mut virus demonstrated a small but significant increase in the infection of IPMK KOVector target cells compared to the infections of both the WTVector and IPMK KOIPMK-Flag cells (Fig. 3B, green dashed line), suggesting that the combination of mutations in the CA 5-mut capsid may be beneficial to infection of IP6-depleted target cells.