The results of Kaplan–Meier survival curves showed that high/low expression (more or less than median of expression value, respectively) of five nodes (GPM6A, METTL24, SCN7A, HAND2‐AS1, PDZRN4) could significantly clarify rectal cancer patients into two groups with different survival outcomes by the threshold of log‐rank test p < 0.05 (Figure 2d). Here, HAND2 is linked to rectal cancer.