COQ2 and multiple system atrophy: A loss-of-function mutation in the gene COQ2, which encodes for the coenzyme Q10 (COQ10), has been reported in Japanese familial and sporadic MSA cases, as well as other East Asian countries (Multiple-System Atrophy Research Collaboration 2013; Ogaki et al. 2014; Quinzii et al. 2014; Lin et al. 2015; Zhao et al. 2016).