Other studies have proposed genetic variants for increased MSA susceptibility, such as GBA (Mitsui et al. 2015), SLC1A4, SQSTM1, and EIF4EBP1 (Soma et al. 2008), and LRRK2 (Heckman et al. 2014; Lee et al. 2018; Riboldi et al. 2019), Some of these risk variants were also found in multiplex families where MSA coincided with PD and suggests some overlap in genetic risk between diseases (Mitsui et al. 2015). This evidence concerns the gene LRRK2 and multiple system atrophy.