EWSR1 and hepatocellular carcinoma: In addition, immunohistochemical analysis of EWSR1 in our cohort showed low expression in all the healthy liver samples (124/124) whereas it was overexpressed in 81.45% (101/124) of the HCC tissues, suggesting that EWSR1 is upregulated in HCC (P< 0.001, Figure 1(c)), which is consistent with data from TCGA and GEO databases.