EWSR1 and hereditary clear cell renal cell carcinoma: As mentioned before, EWSR1 is well-known to be able to fuse with a range of genes in the mesenchymal neoplasms, and a few series of epithelial tumors as myoepithelial[22], primary clear cell carcinoma of the thymus [23] and the Xp11 translocation renal cell carcinoma [24].