IL1B and viral infectious disease: Accordingly, aberrant astrogenesis is prevented in theabsence of IL-1 signaling in NSC, indicating that only newly generated astrocytes exertneurotoxic effects, preventing synapse repair and promoting spatial learning deficits.Ex vivo evaluation of IL-1β-treated adult hippocampal NSC revealed theupregulation of developmental differentiation pathways that derail adult neurogenesis infavor of astrogenesis, following viral infection.