In our previous study, the gene expressions of MMP1, MMP3, ADAMTS4, ADAMTS5, CXCL5, and IL‐6 were up‐regulated in NP tissue 1 day after one strike loading, and the gene expressions of MMP1, MMP13, and ADAMTS5 were upregulated in AF tissue 8 days after one strike loading. The gene discussed is ADAMTS5; the disease is atrial fibrillation.