Our novel observations include correlation between BRCA1 mRNA-high tumor expression and age <45 years at CRC diagnosis, BRCA1 mRNA-low expression and basal BC, mucinous adenocarcinoma among BRCA1 mRNA-low CRC, and higher frequency of males in BRCA1 mRNA-high BC and CRC. This evidence concerns the gene BRCA1 and colon mucinous adenocarcinoma.