CD274 and neoplasm: Using the combined positive score to assess PD-L1 expression on tumor and immune cells, digital image analyses and pathologists’ interpretations on stained slides (using the 22C3 pharmDx assay [Dako, Denmark]) demonstrated 33 (84.6%) of 39 cases had concordant results, and statistical analyses indicated that PD-L1 expression interpreted by pathologists or digital image analysis did not differ significantly for predicting responses to pembrolizumab112.