Highly expressed in MetS are mRNAs for the lectin complement pathway related serine proteases MASP-1 (p = 0.018) and MASP-2 (p = 0.049) while the expression of properdin (p = 0.026) and factor B, CFB (p = 0.002) from the alternative complement pathway (AP) are significantly diminished and factor D, CFD (n = 4, p = 0.035) is highly expressed (Fig. 4a). The gene discussed is CFD; the disease is metabolic syndrome.