Conversely, the prostacyclin synthase, PTGIS (p = 0.0305) from the arachidonic pathway as well as the antioxidant defense involved glutathione peroxidase, peroxiredoxin 2, PRDX2 (p = 0.0092) are strikingly diminished in MetS. This evidence concerns the gene PRDX2 and metabolic syndrome.