On the other hand, although Iba-1 is expressed in all retinal layers of both treated and untreated AD mice, the anti-inflammatory cytokine IL-10 is strongly expressed and colocalized with Iba-1 in the RPE and OPL retinal layers of mice treated with anti-TNFSF10 (Fig. 6D, F, Supplementary Fig. 5B, Supplementary Fig. 6). The gene discussed is AIF1; the disease is Alzheimer disease.