ENO2 and multiple system atrophy: Meta-analysis did not show any significant changes in CSF NSE levels in MSA (Hedges’ g = 0.387, 95% CI −0.293 to 1.067, p = 0.2648; Fig. 6), although the data displayed very high heterogeneity (Q = 20.63, df = 3, p = 0.0001, I2 = 85.46%).