ENO2 and multiple system atrophy, cerebellar type: Furthermore, sub-group analyses of MSA-C and MSA-P without the data from the study by Santaella et al. [26] were performed because sub-group data were not reported in the latter study, but no significant changes in CSF NSE levels were detected in either group (MSA-C: Hedges’ g = 0.412, 95% CI −0.654 to 1.479; MSA-P: Hedges’ g = −0.006, 95% CI −0.577 to 0.566; see Additional file 5).