CHI3L1 and multiple system atrophy: Recent studies have identified other potentially useful biomarkers of MSA, such as α-synuclein, neurofilament light chain, DJ-1, 8-hydroxyguanosine (8OHG), Fms-related tyrosine kinase ligand (Flt3L), YKL-40 (also known as chitinase-3-like protein 1; CHI3L1), and ubiquitin carboxy-terminal hydrolase L1 (UCHL-1) [36].