We performed RNA pulldown to search for potential NEAT1_1 associated proteins, finding that cytoplasmic disheveled 2 (DVL2) and E3 ubiquitin ligase Trim56 interacted with NEAT1_1 in both human and murine AML cells (Figure 6A,B; Figure S5A, Supporting Information). The gene discussed is DVL2; the disease is acute myeloid leukemia.