IL6 and multiple sclerosis: This transient increase in choroidal IL-6 mRNA is similar to that observed for plasma IL-6 following strenuous exercise (Ostrowski et al., 1998), following ischemic brain injuries (Hagberg et al., 1996; Fassbender et al., 1994), surgical trauma (Nishimoto et al., 1989), and in a subset of patients with multiple sclerosis following treatment with interferon-β (Nakatsuji et al., 2006).