To clarify the effect of miR-23a-3p on the inflammatory cytokines IL-6 and TNF-α, as well as the fibrotic indicator FN in DKD, we transfected HK-2 cells with the miR-23a-3p mimic and the miR-23a-3p inhibitor and evaluated the effect by qRT-PCR and Western blot analysis. Here, TNF is linked to diabetic kidney disease.