Similarly, analysis of endpoint tumors in Mrb-OVA alone treated mice (online supplemental figure 2) revealed that the endogenous tumor-specific CD8+ T cells (marked by OVA tetramer staining) showed high CXCR6 expression compared with non-specific (OVA tetramer negative) T cells (online supplemental figure 3A). Here, CXCR6 is linked to neoplasm.