To explore the mechanism of miR-942-5p affecting PD, the SH-SY5Y cells were transfected with mimic control, miR-942-5p mimic, miR-942-5p mimic + control plasmid, or miR-942-5p mimic + NAIF1 plasmid for 48 h, and then treated with 1 mM MPP+ for 24 h. The gene discussed is NAIF1; the disease is Parkinson disease.