In the present experiment, the protein expression levels of hypertrophic markers, including atrial natriuretic peptides (ANP), B-type natriuretic peptides (BNP), and β-myosin heavy chain (MHC), were increased by TAC surgery in TAC group mice (p < 0.001) (Figure 3(A)). The gene discussed is HLA-C; the disease is persistent truncus arteriosus.