in the GI tract positively correlated with several chronic disorders, including nonalcoholic fatty liver disease,17 atherosclerotic cardiovascular disease,18 and CRC.19 Although a recent study has demonstrated that an infant isolate K. pneumoniae 51–5 (ST1243) increases colon tumors in ApcMin/+; Il10−/- mice,20 it is still unclear whether K. pneumoniae is considered a pro-carcinogen of CRC. The gene discussed is IL10; the disease is colonic neoplasm.