Among the colorectal tumorigenic features analyzed, including the rates of cells positive for Ki-67 or β-catenin, suppression of carbonic anhydrase II, and the loss of goblet cells (Figure 2b,c), a significantly higher level of nucleo-cytoplasmic distribution of β-catenin was detected in the adenomas produced in the AOM-DSS-ST11 K. pneumoniae mice than that in the AOM-DSS-alone group (Figure 2d). This evidence concerns the gene CA2 and infectious otitis media.