However, our results and a recent study from another group34 both suggested that PALB2 conferred 5-fold increased risk for breast cancer in Chinese women, indicating that the risk associated with the PALB2 gene was lower than that of BRCA1/2 genes in Chinese women, although the magnitude of risk for the PALB2 gene reached the threshold of high risk genes. This evidence concerns the gene BRCA1 and breast carcinoma.