However, our previous study based on the kin-cohort method found that the cumulative breast cancer risks in BRCA1/2 carriers up to the age of 70 years were 37.9% and 36.5% in Chinese women, respectively43, which were also 10-fold higher risks than noncarriers (3.6% by the age of 70 years). The gene discussed is BRCA1; the disease is breast cancer.