BDNF, GDNF, and NGF are the most abundant neurotrophins that existed in CNS and involved in the pathophysiology of mood and other stress-related disorders (Bjorkholm & Monteggia 2016, Castren & Kojima 2017, von Bohlen Und Halbach & von Bohlen Und Halbach 2018). Here, GDNF is linked to stress-related disorder.