The constitutive overexpression of c‐Myc in these two cell lines significantly increased the cell viability (Figure 2B and Appendix A1 and Figure S4B, Supporting Information), restored the cell cycle progression (Figure 2C and Appendix A1 and Figure S4C, Supporting Information), and protected the cells against apoptotic cell death (Figure 2D and Appendix A1 and Figure S4D, Supporting Information) in the presence of SR140333, confirming that c‐Myc mediates for the response to SR140333 in human CRC cells. Here, MYC is linked to colorectal carcinoma.