TACR1 and neoplasm: A combination of NK‐1R antagonists with chemotherapy/radiotherapy was reported to reduce the side effects of conventional cancer therapy and improved the antitumor effects.[24, 33] In this study, we demonstrated that treatment with NK‐1R antagonists not only induced apoptosis and inhibited tumor growth but also improved the efficacy of the chemotherapeutic drug 5‐fluorouracil in CRC.