LGR5 and cancer: We found that high CCNP expression correlated with a high expression of Axin2 (p < 0.0001), cyclin D1 (CCND1) (p = 0.0026), Lgr5 (p < 0.0001) and Ascl2 (p < 0.0001), suggesting that CCNP and stemness are broadly intertwined in human cancer.