In the present research, the levels of the inflammatory factors TNF-α, IL-6, and MPO were determined, and it was found that the levels of these three factors in the mimics group were obviously higher than those in the other two groups, while their levels declined distinctly in the inhibitors group, illustrating that there are massive inflammatory factors in the pulmonary tissues of pulmonary fibrosis mice and that miRNA-30a-5p inhibitors can repress the production of inflammatory factors in pulmonary factors. This evidence concerns the gene MPO and pulmonary fibrosis.