NPPA and heart disorder: Blood biomarkers indicating myocardial injury, such as atrial natriuretic peptide (ANP), B-type natriuretic peptide (BNP), creatine phosphokinase (CK-MB), lactate dehydrogenase (LDH), and alkaline phosphatase (ALP) have been exposed to be abnormally changed in SD relevant cardiac diseases (4–7).