At 24 h after transient cerebral ischemia (2 h ischemia/reperfusion), JQ1-treated rats exhibit a marked reduction in neurological deficits, infarct volume, and expression of pro-inflammatory mediators IL-1β, IL-6, IL-17, and TNF-α in the ischemic brain (Liu et al., 2017). The gene discussed is TNF; the disease is transient ischemic attack.