EZH2 and neoplasm: Further studies revealed that EZH2 inhibits the expression of ET microRNAs (miRNAs) (EZH2-targeted miRNAs) through the H3K27me3 pathway, thus forming a positive feedback loop of EZH2 miRNAs, maintaining the high expression of EZH2 and promoting the proliferation of tumor cells by regulating key growth inhibitory factors.