ADAM12 and colon adenocarcinoma: Unexpectedly, we newly identified some studies (GSE17536-Smith and GSE14333-Jorissen) that showed a correlation between low ADAM12 expression and a shorter OS (n = 177, HR = 0.034, COX-P = 0.042) and DFS (n = 145, HR = 0.41, COX-P = 0.0027; n = 226, HR = 0.27, COX-P = 0.010; n = 226, HR = 0.23, COX-P = 0.017) for patients with COAD (Figures 4E–H).