Using the interactive Venn diagram to analyze the difference between the two datasets, our results indicated that ADAM12 expression in COAD was strongly correlated with the Periostin (POSTN), Matrix metallopeptidase 14 (MMP14), Integrin subunit beta 1 (ITGB1), TIMP metallopeptidase inhibitor 2 (TIMP2), and Matrix metallopeptidase 2 (MMP2) genes (Figure 6B). Here, ITGB1 is linked to colon adenocarcinoma.