In our results, ADAM12 expression was significantly negatively correlated with tumor purity (Cor=-0.404, P=2.03e-17) and was significantly positively correlated with CD8+ T cells (partial cor=0.285, P=4.73e-09), CD4+ T cells (partial cor=0.386, P=9.43e-16), macrophages (partial cor=0.597, P=2.64e-40), neutrophils (partial cor=0.557, P=5.51e-37), and dendritic cells (partial cor=0.555, P=7.53e-34) (Figure 9A). This evidence concerns the gene CD8A and neoplasm.