It was concluded that the MMP14 expression of 33 tumors and the immune score (ImmuneScore) relationship showed a significant correlation (p < 0.05), as the expression of MMP14 and the immune score were positively related in BLCA, BRCA, CESC (cervical cancer), COAD, lymphoid neoplasm diffuse large B-cell lymphoma (DLBC), ESCA, GBM, HNSC, KICH, KIRP, LGG, LIHC, LUAD, LUSC, OV, PAAD, pheochromocytoma and paraganglioma (PCPG), PRAD, READ, STAD, and THCA. The gene discussed is MMP14; the disease is hereditary pheochromocytoma-paraganglioma.