Figure 1A shows the incidence of copy number variation and somatic mutations of the m6A regulatory factors in bladder cancer. Figure 1B shows the mutation frequency of each gene obtained by statistical analysis of the copy number of m6A. Figure 1C shows the m6A copy number circle diagram, which shows the position of the CNV mutation of the m6A regulatory factor on the chromosome. Figure 1D represents a further analysis of the m6A difference. This evidence concerns the gene METTL3 and urinary bladder carcinoma.