As shown in Supplementary Table 2, we found that the variant alleles G and A of the two SNPs (rs10420388 and rs10418574) in CLPP were associated with an increased risk of squamous cell carcinoma (OR = 1.07 and 1.07; P = 0.013 and 0.016, respectively), while the variant allele T of SNP rs11126435 in M1AP was associated with a decreased risk of adenocarcinoma (OR = 0.95; P = 0.027). The gene discussed is CLPP; the disease is squamous cell carcinoma.