Allergy to peanut is among the common causes of food-allergy-related anaphylaxis and emergency department admissions [1, 2] The diagnosis of a patient with suspected peanut allergy may include a careful history taking, skin-prick testing, measurement of serum-specific IgE, and, possibly, an oral food challenge, all of which are discussed in Part 2 of this white paper (Blum et al. This evidence concerns the gene IGHE and Allergy.