MTFR1 and myocardial infarction: Suppressing MTFR1 translation attenuates mitochondrial fission, apoptosis and myocardial infarction (Wang et al., 2015), which indicates that excessive expression of MTFR1 aggravates mitochondrial fission and apoptosis, meanwhile regulating MTFR1might afford protection against oxidative stress-induced endothelial progenitor cell injury (Chen et al., 2019).