With linear regression analysis for LVM as a dependent factor, there was a nonsignificant prediction of age, serum sclerostin, aortic valve calcification, and mitral valve calcification for LVM; on the other hand, hypertension had a significant positive independent prediction for LVM, while serum HDL and serum DDK-1 were negative significant independent indicators for LVM. This evidence concerns the gene SOST and aortic valve calcification.