With linear regression analysis for LVM as a dependent factor, there was a nonsignificant prediction of age, serum sclerostin, aortic valve calcification, and mitral valve calcification for LVM; on the other hand, hypertension had a significant positive independent prediction for LVM, while serum HDL and serum DDK-1 were negative significant independent indicators for LVM. The gene discussed is MGME1; the disease is Hypertension.