Probably, the obtained data can be explained by the fact that a low level of neutrophil activity associated with the presence of the AG genotype of rs5743551 (TLR1) and GG genotype of rs4986790 (TLR4) is a marker of a violation of the genetically determined mechanism of innate immunity and can be a predictor of the lethal outcome of pneumonia. This evidence concerns the gene TLR4 and pneumonia.