According to our KM survival curve analysis, we found that high expression of CDK1, CDC20, BUB1, BUB1B, CCNB1, NDC80, CENPF, MAD2L1, and NUF2 predicted worse survival outcome in patients with HCC (P < 0.05), but CCNB2 did not. This evidence concerns the gene CCNB1 and hepatocellular carcinoma.