AKT1 and atherosclerosis: Basic studies have shown that quercetin also has anti-inflammatory [36], antiapoptotic [37], antioxidative stress damage [38], promotes angiogenesis [38], and prevents atherosclerosis [39, 40], with targets such as iNOS, caspase-3, antioxidant enzymes, Nrf2, MMP-9, NF-κB, and PARP [39, 41–46], involving signaling pathways such as PGC-1 alpha [47], NF-κB [48], and Akt.