SLAIN2 and colorectal carcinoma: In addition, among the top upregulated miRNAs, miR-106b has been reported to be correlated with malignant behavior of CRC cells by targeting FJX1 [40] and SLAIN2 [41], the levels of which were not changed after DiAsSpm treatment, suggesting miR-641 and miR-106b might not be the major contributors to the proliferative property of CRC cells after DiAcSpm treatment.