Consistently, BOP1 was consistently upregulated in paired tumor samples compared with adjacent normal samples in 16 malignancies, including BRCA, BLCA, COAD, CHOL, HNSC, ESCA, LIHC, KIRC, KIRP, LUSC, LUAD, UCEC, THCA, STAD, READ, and PRAD (P < 0.05) (Figure 2). This evidence concerns the gene BOP1 and neoplasm.