The presence of epigenetic changes of Wnt5a, including methylation, in different stages of some cancers such as colorectal cancer (CRC) has shown that aberrant methylation levels of Wnt5a are not significantly correlated with clinicopathological characteristic including maximal tumor size, tumor extent, tumor site, histology, and Dukes stage [39]. Here, WNT5A is linked to colorectal carcinoma.