Specifically, we identified that 10 m6A regulators including 3 writers (KIAA1429, ZC3H13, and RBM15) and 7 readers (YTHDF3, IGF2BP2, HNRNPA2B1, HNRNPC, RBMX, YTHDF1, and IGF2BP3) were upregulated in COAD samples at both mRNA and protein levels (Figures 1A,B, adjusted p-value < 0.05), as compared with the adjacent normal tissues. This evidence concerns the gene YTHDF3 and colon adenocarcinoma.