In a study by Beckwitt et al. (2018) Akt phosphorylation was decreased by treatment of atorvastatin in three breast cancer cell lines, i.e., MCF-7 RFP, MDA-MB-231 RFP, and MDA-MB-231 RFP/Ecad, and this inhibition was shown even after stimulation with growth factor EGF. This evidence concerns the gene AKT1 and breast carcinoma.