ADRA1A and hypertrophic cardiomyopathy: GSEA analysis results showed that down-regulated hub genes IL-1B, IL-1A, and CXCL4 were enriched in the ubiquitin-mediated proteolysis signal pathway and oxidative phosphorylation pathway related to biological behavior (Figure 6A); the upregulated hub genes ADRA1A, AVPR1B, and OPN4 were enriched in the calcium signal pathway, extracellular matrix (ECM) receptor interaction, dilated cardiomyopathy, and hypertrophic cardiomyopathy (Figure 6B).