Furthermore, the secretion of IL-1β and IL-18 from J774A.1 cells (Figure 6D) and PECs (Figure 6M) in the S. aureus infection group was significantly increased compared with that in the noninfection group, while in comparison, the expression level of IL-1β and IL-18 in BAY pretreatment infection group was significantly decreased. Here, IL18 is linked to infection.